New meta study reconfirms accuracy of colon capsule endoscopy

In their article “Diagnostic Accuracy for Per-Patient Polyp Detection of Second-Generation Capsule Endoscopy Compared to Colonoscopy: A Meta-Analysis of Multicenter Studies”, Hassam Ali, Rahul Pamarthy, Shiza Sarfraz, and Eslam Ali compare the outcomes of 5 multicenter studies that analyzed the accuracy of CCE vs colonoscopy.

While the usual challenges continue to be reported, especially the ability to achieve well prepped, complete passage procedures, the ability to accurately detect relevant polyps is not questioned anymore, with specificity being well with typical interobserver variance in colonoscopies. What remains are the questions on how to deal with the information generated by the procedures, specifically:

What to do with diminutive polyps?
The answer to that question might be more driven by policies and economics than by clinical insights. However, they should be answered soon to see the outcomes everybody is aspiring too: More capacity for digestive disease diagnostics with higher patient satisfaction at lower prices.

Reference:
Ali, Hassam, Rahul Pamarthy, Shiza Sarfraz, and Eslam Ali. “Diagnostic Accuracy for Per-Patient Polyp Detection of Second-Generation Capsule Endoscopy Compared to Colonoscopy: A Meta-Analysis of Multicenter Studies.” Cureus 13, no. 8 (August 30, 2021). https://doi.org/10.7759/cureus.17560.


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